Generic substitution in the treatment of epilepsy: case evidence of breakthrough seizures.

@article{Berg2008GenericSI,
  title={Generic substitution in the treatment of epilepsy: case evidence of breakthrough seizures.},
  author={Michael J Berg and Robert A. Gross and Kenneth J Tomaszewski and Wendy M Zingaro and Lisa S Haskins},
  journal={Neurology},
  year={2008},
  volume={71 7},
  pages={525-30}
}
OBJECTIVE There are concerns that generic and brand antiepileptic drugs (AEDs) may not be therapeutically equivalent. This study investigated how generic AED substitution may have negative consequences. METHODS Sixty-nine of 150 physicians who participated in a large survey on generic AED substitution completed a case review form regarding a patient who experienced a loss of seizure control due to a generic AED. Nineteen were excluded from analysis. RESULTS Fifty patients, well-controlled… CONTINUE READING

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References

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Showing 1-10 of 19 references

Mandatory generic substitution of antiepileptic drugs raises concerns

C. Cassels
Available at: http://www. medscape.com/viewarticle/548860. Accessed May • 2006

Physician and patients perceive that generic drug substitution of antiepileptic drugs can cause break through seizures: results form a US survey

MJ Berg, R. Gross
Epilepsia 2006;47(suppl • 2006

Generic substitution for brand name antiepileptic drugs: a survey.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques • 2000

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