Generic cyclosporine formulations: more open questions than answers.

@article{Cattaneo2005GenericCF,
  title={Generic cyclosporine formulations: more open questions than answers.},
  author={Dario Cattaneo and Norberto Perico and Giuseppe Remuzzi},
  journal={Transplant international : official journal of the European Society for Organ Transplantation},
  year={2005},
  volume={18 4},
  pages={
          371-8
        }
}
  • Dario Cattaneo, Norberto Perico, Giuseppe Remuzzi
  • Published in
    Transplant international…
    2005
  • Medicine
  • The introduction of cyclosporine (CsA) in clinical practice has significantly improved patient and allograft survival after organ transplantation. The new microemulsion CsA formulation, Neoral, has been associated with a more reproducible absorption and a better patient outcome as compared to the old formulation Sandimmune. Recently, several generic CsA formulations have been tested as bioequivalent to Neoral. Bioequivalence tests have been performed in selected groups of young, healthy male… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 54 REFERENCES

    Neoral-to-Gengraf conversion in renal transplant recipients.

    VIEW 5 EXCERPTS
    HIGHLY INFLUENTIAL

    Report of the American Society of Transplantation conference on immunosuppressive drugs and the use of generic immunosuppressants.

    VIEW 7 EXCERPTS
    HIGHLY INFLUENTIAL

    Immunosuppression: practice and trends.

    • Dixon B Kaufman, Ron Shapiro, +3 authors David Dyke
    • Medicine
    • American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
    • 2004
    VIEW 1 EXCERPT

    The value of C2 monitoring in stable renal allograft recipients on maintenance immunosuppression.

    • Gunilla Einecke, Ingrid Mai, +4 authors Klemens Budde
    • Medicine
    • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
    • 2004
    VIEW 2 EXCERPTS

    Comparison of two cyclosporine formulations in healthy Middle Eastern volunteers: bioequivalence of the new Sigmasporin Microoral and Sandimmun Neoral.

    • Naji M. Najib, Nasir M Idkaidek, +6 authors Qumaruzaman
    • Medicine
    • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
    • 2003
    VIEW 1 EXCERPT