Generative-Discriminative Basis Learning for Medical Imaging

@article{Batmanghelich2012GenerativeDiscriminativeBL,
  title={Generative-Discriminative Basis Learning for Medical Imaging},
  author={Nematollah Batmanghelich and Ben Taskar and Christos Davatzikos},
  journal={IEEE Transactions on Medical Imaging},
  year={2012},
  volume={31},
  pages={51-69}
}
This paper presents a novel dimensionality reduction method for classification in medical imaging. The goal is to transform very high-dimensional input (typically, millions of voxels) to a low-dimensional representation (small number of constructed features) that preserves discriminative signal and is clinically interpretable. We formulate the task as a constrained optimization problem that combines generative and discriminative objectives and show how to extend it to the semi-supervised… CONTINUE READING

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