Generation of thalamic neurons from mouse embryonic stem cells.

  title={Generation of thalamic neurons from mouse embryonic stem cells.},
  author={Atsushi Shiraishi and Keiko Muguruma and Yoshiki Sasai},
  volume={144 7},
The thalamus is a diencephalic structure that plays crucial roles in relaying and modulating sensory and motor information to the neocortex. The thalamus develops in the dorsal part of the neural tube at the level of the caudal forebrain. However, the molecular mechanisms that are essential for thalamic differentiation are still unknown. Here, we have succeeded in generating thalamic neurons from mouse embryonic stem cells (mESCs) by modifying the default method that induces the most-anterior… CONTINUE READING
1 Citations
58 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 58 references

embryonic stem cells: from neurogenesis to histogenesis

  • T. Nagai, K. Ibata, E. S. Park, M. Kubota, K. Mikoshiba, A. Miyawaki
  • Dev. Growth Differ
  • 2002
Highly Influential
5 Excerpts

morphogenetic protein 4 in mammalian mesoderm and hematopoietic development

  • C. Kiecker, A. Lumsden
  • Mol. Cell. Biol
  • 2004
Highly Influential
4 Excerpts

ES cell culture induces rostral hypothalamic differentiation

  • M. F. Wells, R. D. Wimmer, L. I. Schmitt, G. Feng, M. M. Halassa
  • Proc. Natl. Acad. Sci. USA
  • 2016
1 Excerpt

Similar Papers

Loading similar papers…