Generation of resting membrane potential.

@article{Wright2004GenerationOR,
  title={Generation of resting membrane potential.},
  author={Stephen H. Wright},
  journal={Advances in physiology education},
  year={2004},
  volume={28 1-4},
  pages={
          139-42
        }
}
  • S. Wright
  • Published 1 December 2004
  • Biology
  • Advances in physiology education
This brief review is intended to serve as a refresher on the ideas associated with teaching students the physiological basis of the resting membrane potential. The presentation is targeted toward first-year medical students, first-year graduate students, or senior undergraduates. The emphasis is on general concepts associated with generation of the electrical potential difference that exists across the plasma membrane of every animal cell. The intention is to provide students a general view of… 

Figures and Tables from this paper

Generation and propagation of the action potential.
A model for controlling the resting membrane potential of cells using nanoparticles
TLDR
A novel dynamical system model is presented that allows parameters related to permeabilities of ion channels to be controlled so the resting membrane potential reaches a desired value and is able to explain the decreased polarity across the cell membrane when nanoparticles are introduced in the vicinity of a cell.
A model for membrane potential and intracellular ion distribution.
Understanding the electrical behavior of the action potential in terms of elementary electrical sources.
TLDR
The proposed model, which incorporates intuitive graphical representations, has improved students' understanding of the electrical potentials generated by bioelectrical sources and has heightened their interest in bioelectricity.
Probing the membrane potential of living cells by dielectric spectroscopy
TLDR
A quantitative way to measure the membrane potential of live cells by dielectric spectroscopy is demonstrated and the values obtained are in good agreement with those obtained using traditional methods—voltage-sensitive dyes.
The critical role of logarithmic transformation in Nernstian equilibrium potential calculations.
TLDR
The membrane potential, arising from uneven distribution of ions across cell membranes containing selectively permeable ion channels, is of fundamental importance to cell signaling and the concept of the equilibrium potential is vital to understanding the origins of the membrane potential.
Bioelectric signaling as a unique regulator of development and regeneration.
TLDR
Evidence that bioelectric cues play defined instructional roles in orchestrating development and regeneration is reviewed, and key areas in which to refine the understanding of this signaling mechanism are outlined.
An intuitive approach to understanding the resting membrane potential.
  • D. Cardozo
  • Biology
    Advances in physiology education
  • 2016
a fundamental property of cells is that through the use of ion transporters they maintain intracellular ion concentrations that differ from those of the extracellular environment ([15][1]). Although
Donnan effect on chloride ion distribution as a determinant of body fluid composition that allows action potentials to spread via fast sodium channels
  • S. Kurbel
  • Biology
    Theoretical Biology and Medical Modelling
  • 2011
Proteins in any solution with a pH value that differs from their isoelectric point exert both an electric Donnan effect (DE) and colloid osmotic pressure. While the former alters the distribution of
...
1
2
3
4
5
...