Generation of pluripotent stem cells via protein transduction.

  title={Generation of pluripotent stem cells via protein transduction.},
  author={Xia Li and Pengfei Zhang and Chao Wei and Yunhai Zhang},
  journal={The International journal of developmental biology},
  volume={58 1},
The development of techniques for reprogramming somatic cells led to the birth of the cloned sheep “Dolly” and the generation of induced pluripotent stem cells (iPSCs). iPSCs hold great promise for in vitro disease modeling, new drug screening, regenerative medicine and agricultural production. These cells can differentiate into almost any tissue types and they can be used to produce autografts that will not be rejected by the patient. However, practical application has been limited by the… CONTINUE READING