• DOI:10.1126/science.1553558
Corpus ID: 17905159

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.

@article{Reynolds1992GenerationON,
  title={Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.},
  author={Brent A Reynolds and Samuel Weiss},
  journal={Science},
  year={1992},
  volume={255 5052},
  pages={
          1707-10
        }
}

Brent A Reynolds, Samuel Weiss

Published in Science 1992

Biology, Medicine

Neurogenesis in the mammalian central nervous system is believed to end in the period just after birth; in the mouse striatum no new neurons are produced after the first few days after birth. In this study, cells isolated from the striatum of the adult mouse brain were induced to proliferate in vitro by epidermal growth factor. The proliferating cells initially expressed nestin, an intermediate filament found in neuroepithelial stem cells, and subsequently developed the morphology and antigenic… CONTINUE READING

View PDF

Save to Library

Create Alert

Cite

Launch Research Feed