Generation of monoclonal antibodies reacting with human epithelial ovarian cancer.

  title={Generation of monoclonal antibodies reacting with human epithelial ovarian cancer.},
  author={Elda Tagliabue and Sylvie M{\'e}nard and Gabriella Della Torre and Piero Barbanti and Renato Mariani-Costantini and Giulia Porro and Maria Ines Colnaghi},
  journal={Cancer research},
  volume={45 1},
Fusion of the murine myeloma line P3-X63-Ag8-U1 with spleen cells from a mouse immunized with a membrane preparations (CM) of a mucinous ovarian cystoadenocarcinoma yielded two monoclonal antibodies, MOv1 and MOv2, which reacted by solid-phase radioimmunoassay with immunizing tumor CM but were unreactive with normal kidney CM as well as with plasma proteins and peripheral blood cells from the immunizing carcinoma patient. MOv1 and MOv2 were further tested by solid-phase radioimunoassay on a… CONTINUE READING
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Ovarian Pathology

Current Topics in Pathology • 1989
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