Generation of monoclonal anti-digoxin antibodies.

  title={Generation of monoclonal anti-digoxin antibodies.},
  author={Ivan R Kehayov and S N Tyutyulkova and Stephan Radoslavov Lolov and Stanimir Dobrev Kyurkchiev},
  volume={9 5},
Anti-digoxin monoclonal antibodies are a useful model for basic immunochemical studies, for investigation of endogenous digoxin-like substances and in immunoassay for cardiac glycosides. The complete phenotypic characterization is a requisite for the selection of antibodies with desired binding parameters for different purposes. Twenty-two high-affinity monoclonal antibodies specific for digoxin were obtained in two fusion experiments. Treatment of antigen-antibody complex with potassium… CONTINUE READING

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