Generation of mice with a conditional allele for the p75(NTR) neurotrophin receptor gene.

@article{Bogenmann2011GenerationOM,
  title={Generation of mice with a conditional allele for the p75(NTR) neurotrophin receptor gene.},
  author={Emil Bogenmann and Penny S. Thomas and Qianfeng Li and Jieun E. Kim and L X Yang and Brian A Pierchala and Vesa M Kaartinen},
  journal={Genesis},
  year={2011},
  volume={49 11},
  pages={862-9}
}
The p75(NTR) neurotrophin receptor has been implicated in multiple biological and pathological processes. While significant advances have recently been made in understanding the physiologic role of p75(NTR) , many details and aspects remain to be determined. This is in part because the two existing knockout mouse models (Exons 3 or 4 deleted, respectively), both display features that defy definitive conclusions. Here we describe the generation of mice that carry a conditional p75(NTR) (p75(NTR… CONTINUE READING
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