Generation of intestinal surface: an absorbing tale.

@article{Walton2016GenerationOI,
  title={Generation of intestinal surface: an absorbing tale.},
  author={Katherine D. Walton and Andrew M. Freddo and Sha Wang and Deborah L Gumucio},
  journal={Development},
  year={2016},
  volume={143 13},
  pages={2261-72}
}
The vertebrate small intestine requires an enormous surface area to effectively absorb nutrients from food. Morphological adaptations required to establish this extensive surface include generation of an extremely long tube and convolution of the absorptive surface of the tube into villi and microvilli. In this Review, we discuss recent findings regarding the morphogenetic and molecular processes required for intestinal tube elongation and surface convolution, examine shared and unique aspects… CONTINUE READING
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