Generation of human autologous melanoma-specific cytotoxic T cells from tumor-involved lymph nodes.

Abstract

Cytotoxic T lymphocytes (CTL) specific for autologous human melanoma have been successfully generated in vitro from tumor bearing lymph nodes without any stimulation by the autologous tumor. Tumor-involved lymph node cells (LNC) were cultured in serum free medium (AIM-V) containing 1,000 U/ml of recombinant interleukin-2. The best expansion and specific… (More)

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Cite this paper

@article{Maeda1991GenerationOH, title={Generation of human autologous melanoma-specific cytotoxic T cells from tumor-involved lymph nodes.}, author={Kurane Maeda and Ren{\'e} Lafreni{\`e}re and John Gregory McKinnon and L. Martin Jerry}, journal={Molecular biotherapy}, year={1991}, volume={3 2}, pages={95-102} }