Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation.

@article{Feng2014GenerationOH,
  title={Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation.},
  author={Nianhua Feng and Qin Han and Jing Li and Shihua Wang and Hongling Li and Xinglei Yao and Robert Chunhua Zhao},
  journal={Stem cells and development},
  year={2014},
  volume={23 5},
  pages={
          515-29
        }
}
Neural stem cells (NSCs) are ideal candidates in stem cell-based therapy for neurodegenerative diseases. However, it is unfeasible to get enough quantity of NSCs for clinical application. Generation of NSCs from human adipose-derived mesenchymal stem cells (hAD-MSCs) will provide a solution to this problem. Currently, the differentiation of hAD-MSCs into highly purified NSCs with biological functions is rarely reported. In our study, we established a three-step NSC-inducing protocol, in which… CONTINUE READING

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HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway.

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References

Publications referenced by this paper.
SHOWING 1-10 OF 57 REFERENCES

Sox1 marks an Page 30 of 53 St em C

M Venere, YG Han, +3 authors R Blelloch
  • Development
  • 2012
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