Generation of cells with phenotypes of both intercalated duct-type and myoepithelial cells in human parotid gland adenocarcinoma clonal cells grown in athymic nude mice.

@article{Yanagawa1986GenerationOC,
  title={Generation of cells with phenotypes of both intercalated duct-type and myoepithelial cells in human parotid gland adenocarcinoma clonal cells grown in athymic nude mice.},
  author={Takashi Yanagawa and Yoshitake Hayashi and S Nagamine and Hideo Yoshida and Yoshiaki Yura and Mitsunobu Sato},
  journal={Virchows Archiv. B, Cell pathology including molecular pathology},
  year={1986},
  volume={51 3},
  pages={187-95}
}
A neoplastic epithelial cell line was established from nude mice tumors grown after transplantation of surgical specimens from a human parotid gland adenocarcinoma. This cell line, which had ultrastructure similarities to salivary intercalated duct cells, was found by immunohistochemical techniques to contain amylase, but myosin was not detected. Ultrastructurally, cells of an intermediate type between intercalated ductal and myoepithelial cells were found in the transplanted tumors. Moreover… CONTINUE READING