Generation of an isogenic collection of yeast actin mutants and identification of three interrelated phenotypes.

  title={Generation of an isogenic collection of yeast actin mutants and identification of three interrelated phenotypes.},
  author={Johanna L Whitacre and Dana Davis and Kurt A. Toenjes and S M Brower and Andrea E. Adams},
  volume={157 2},
A large collection of yeast actin mutations has been previously isolated and used in numerous studies of actin cytoskeletal function. However, the various mutations have been in congenic, rather than isogenic, backgrounds, making it difficult to compare the subtle phenotypes that are characteristic of these mutants. We have therefore placed 27 mutations in an isogenic background. We used a subset of these mutants to compare the degree to which different actin alleles are defective in… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 19 references

Role of charged amino acid tosis in Saccharomyces cerevisiae

E. Reisler
Mol . Biol . Cell • 1995
View 3 Excerpts
Highly Influenced

A kinesin - related protein , Smy 1 p , to the same regions of polarized novel fluorescence - activated cell sorter - based screen for yeast en - growth in Saccharomyces cerevisiae

J. M. McCaffery, Q. Xiao, S. D. Emr
Genetics • 1996

Calcium - inde - segment receptors for mating pheromones in yeast

H. Riezman, P. K. Tan, N. G. Davis, G. F. Sprague, F. Schimmoller
J . Cell Biol . pendent calmodulin requirement for endocytosis in yeast . EMBO • 1994

Immunofluorescence localiza - Saccharomyces cerevisiae

D. G. Drubin, D. B. Vinh, H. H. Okamura
Nature • 1994

End 3 andpg 787 , 1998 )

S. Raths, J. Rohrer, F. Crausaz, H. Riezman
Nat . Structural Biol . • 1993
View 1 Excerpt

Characterization of TPM 1 dis - 350 . rupted yeast cells indicates an involvement of tropomyosin in

A. Bretscher
J . Cell Biol . • 1992
View 2 Excerpts

The yeast

S. M. Brower, J. A. Prendergast, R. A. Singer
Genetics • 1991

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