Generation of a proton motive force by histidine decarboxylation and electrogenic histidine/histamine antiport in Lactobacillus buchneri

@article{Molenaar1993GenerationOA,
  title={Generation of a proton motive force by histidine decarboxylation and electrogenic histidine/histamine antiport in Lactobacillus buchneri},
  author={Douwe Molenaar and J S Bosscher and B. ten Brink and Arnold J.M. Driessen and Wilhelmus Nicolaas Konings},
  journal={Journal of Bacteriology},
  year={1993},
  volume={175},
  pages={2864 - 2870}
}
Lactobacillus buchneri ST2A vigorously decarboxylates histidine to the biogenic amine histamine, which is excreted into the medium. Cells grown in the presence of histidine generate both a transmembrane pH gradient, inside alkaline, and an electrical potential (delta psi), inside negative, upon addition of histidine. Studies of the mechanism of histidine uptake and histamine excretion in membrane vesicles and proteoliposomes devoid of cytosolic histidine decarboxylase activity demonstrate that… 

Uniport of anionic citrate and proton consumption in citrate metabolism generates a proton motive force in Leuconostoc oenos

Kinetic analysis of delta pH-driven citrate uptake over a range of external pHs suggests that the monovalent anionic species (H2cit-) is the transported particle, and together, the data show that the transport of citrate is an electrogenic process in which H2cit- is translocated across the membrane via a uniport mechanism.

ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential

ClC transporters may serve as tunable modulators for histamine production by L. reuteri and other gut microbes by promoting long-term colonization and suppression of inflammation and host immune responses.

Histamine, histidine, and growth-phase mediated regulation of the histidine decarboxylase gene in lactic acid bacteria isolated from wine.

Data on histamine-producing lactic acid bacteria isolated from wine should contribute to the prevention of histamine formation during winemaking and storage.

Dual Role for the Tyrosine Decarboxylation Pathway in Enterococcus faecium E17: Response to an Acid Challenge and Generation of a Proton Motive Force

The tyrosine decarboxylation pathway contributes to an acid response mechanism in E. faecium E17, which gives the strain a competitive advantage in nutrient-depleted conditions, as well as in harsh acidic environments, and a better chance of survival, which contributes to higher cell counts in food fermentation products.

The Mechanism of the Tyrosine Transporter TyrP Supports a Proton Motive Tyrosine Decarboxylation Pathway in Lactobacillus brevis

It is proposed that tyrosine decarboxylation in L. brevis results in proton motive force generation by an indirect proton pumping mechanism.

Role of scalar protons in metabolic energy generation in lactic acid bacteria

It is concluded that the generation of a pH gradient, inside alkaline, upon the addition of a weak acid to cells is diagnostic for an electrogenic uptake mechanism translocating negative charge with the weak acid.

Electrogenic glutamine uptake by Peptostreptococcus anaerobius and generation of a transmembrane potential

It appeared that the low-affinity glutamine transport was an electrogenic mechanism which was converting a chemical gradient of glutamine-1 into a delta psi, and other mechanisms of delta psi generation (electrogenic glutamines-pyroglutamate or -ammonium exchange) could not be demonstrated.

Exchange of Aspartate and Alanine

Findings are consistent with operation of a proton-motive metabolic cycle during aspartate metabolism by Lactobacillus subsp.

ADI pathway and histidine decarboxylation are reciprocally regulated in Lactobacillus hilgardii ISE 5211: proteomic evidence

Rec reciprocal interactions between amino acid decarboxylation and the arginine deiminase and ADI routes offer clue keys to the understanding of the accumulation of lactate, amine, ammonia and ethylcarbamate in wine, with consequent implications on different health risk controls.

The role of transport processes in survival of lactic acid bacteria, Energy transduction and multidrug resistance

In Lactococcus lactis three toxin excretion systems have been characterized: cationic toxins can be excreted by a toxin/proton antiport system and by an ABC-transporter, and for anions an ATP-driven ABC-likeexcretion systems exist.
...

References

SHOWING 1-10 OF 28 REFERENCES

Identification, purification, and reconstitution of OxlT, the oxalate: formate antiport protein of Oxalobacter formigenes.

Lactate efflux-induced electrical potential in membrane vesicles of Streptococcus cremoris

The results indicate that lactate efflux is an electrogenic process by which L-lactate is translocated with more than one proton in response to a valinomycin-induced potassium diffusion gradient.

arcD, the first gene of the arc operon for anaerobic arginine catabolism in Pseudomonas aeruginosa, encodes an arginine-ornithine exchanger

It is concluded that the ArcD protein is a transport system that catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in theArginine deiminase pathway.

Regulation of arginine-ornithine exchange and the arginine deiminase pathway in Streptococcus lactis

The results confirm studies of arginine and ornithine transport in membrane vesicles of S. lactis and match the ADI pathway most probably by adjusting the intracellular levels of Ornithine and Arginine.

Malolactic fermentation: electrogenic malate uptake and malate/lactate antiport generate metabolic energy

The experiments described suggest that the generation of metabolic energy during malolactic fermentation arises from electrogenic malate/lactate antiport and electrogenIC malate uptake (in combination with outward diffusion of lactic acid), together with proton consumption as result of decarboxylation of L-malate.

Transport of diamines by Enterococcus faecalis is mediated by an agmatine-putrescine antiporter

Kinetic analysis revealed competitive inhibition for uptake between putrescine and agmatine, and this transport system functionally resembled the previously described arginine-ornithine antiport, which was exclusively induced when the cells were grown in the presence of arginines.

Tyrosine and Histidine Decarboxylase Activities of Pediococcus cerevisiae and Lactobacillus Species and the Production of Tyramine in Fermented Sausages

In investigating formation of tyramine and histamine in a model system, it was found that four commercial sausage starter cultures did not exhibit appreciable tyrosine or histidine decarboxylase

Nucleotide sequence of the Escherichia coli cad operon: a system for neutralization of low extracellular pH

A model for the coupled action of cadA and cadB in uptake of lysine, the reduction of H+ concentration, and excretion of cadaverine is led to.