Generation of a Mig-6 conditional null allele.

Abstract

Mitogen-inducible gene 6 (Mig-6) is a stress-induced gene that serves as a negative regulator of epidermal growth factor (EGF) signaling and acts as a tumor suppressor. Ablation of Mig-6 results in a significant percentage of embryo lethality as well as abnormalities in multiple tissues. To understand the physiological roles of Mig-6, a conditional null… (More)

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Cite this paper

@article{Jin2007GenerationOA, title={Generation of a Mig-6 conditional null allele.}, author={Nili Jin and Jennifer L Gilbert and Russell R. Broaddus and Francesco J. Demayo and Jae-Wook Jeong}, journal={Genesis}, year={2007}, volume={45 11}, pages={716-21} }