Generation of Febrile Seizures and Subsequent Epileptogenesis

@article{Feng2016GenerationOF,
  title={Generation of Febrile Seizures and Subsequent Epileptogenesis},
  author={Bo Feng and Zhong Wen Chen},
  journal={Neuroscience Bulletin},
  year={2016},
  volume={32},
  pages={481-492}
}
  • Bo Feng, Zhong Wen Chen
  • Published in Neuroscience Bulletin 2016
  • Medicine
  • Febrile seizures (FSs) occur commonly in children aged from 6 months to 5 years. Complex (repetitive or prolonged) FSs, but not simple FSs, can lead to permanent brain modification. Human infants and immature rodents that have experienced complex FSs have a high risk of subsequent temporal lobe epilepsy. However, the causes of FSs and the mechanisms underlying the subsequent epileptogenesis remain unknown. Here, we mainly focus on two major questions concerning FSs: how fever triggers seizures… CONTINUE READING

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