Generation and purification of human stem cell-derived cardiomyocytes.

@article{Schwach2016GenerationAP,
  title={Generation and purification of human stem cell-derived cardiomyocytes.},
  author={Verena Schwach and Robert Passier},
  journal={Differentiation; research in biological diversity},
  year={2016},
  volume={91 4-5},
  pages={
          126-38
        }
}
Efficient and reproducible generation and purification of human stem cell-derived cardiomyocytes (CMs) is crucial for regenerative medicine, disease modeling, drug screening and study of developmental events during cardiac specification. Established methods to generate CMs from human pluripotent stem cells (hPSCs) include the Spin-embryoid body (Spin-EB) and monolayer-based differentiation protocol. In the presence of an optimized cocktail of growth factors under defined conditions, hPSCs… CONTINUE READING
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