Generation and modulation of hepatocellular carcinoma circulating cells: a new experimental model.

Abstract

BACKGROUND To establish a new experimental model of human hepatocellular carcinoma by orthotopic implantation of tumoral cells with its subsequent removal, to generate and modulate circulating tumoral cells. MATERIALS AND METHODS Three human hepatoma cell lines (HepG2, PLC/PRF, and Mahlavu) were orthotopically implanted under the Glisson's capsule of the… (More)
DOI: 10.1016/j.jss.2008.03.052

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