Generation and long-term persistence of new neurons in the adult zebrafish brain: A quantitative analysis

@article{Hinsch2007GenerationAL,
  title={Generation and long-term persistence of new neurons in the adult zebrafish brain: A quantitative analysis},
  author={K. Hinsch and G. Zupanc},
  journal={Neuroscience},
  year={2007},
  volume={146},
  pages={679-696}
}
Zebrafish, like other teleosts, are distinguished by their enormous potential to produce new neurons in many parts of the adult brain. By labeling S-phase cells with the thymidine analog 5-bromo-2'-deoxyuridine (BrdU), quantitative analysis demonstrated that, on average, 6000 new cells were generated in the entire adult brain within any 30 min period. This corresponds to roughly 0.06% of the total number of brain cells. Part of these cells underwent a second round of cell division a few days… Expand
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