Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks.

@article{Chang2015GenerationAE,
  title={Generation and evaluation of clade C simian-human immunodeficiency virus challenge stocks.},
  author={Hui-Wen Chang and Lawrence J Tartaglia and James B Whitney and So-Yon Lim and Srisowmya Sanisetty and C. Lavine and Michael S Seaman and Cecelia Rademeyer and Carolyn Williamson and Katharine Ellingson-Strouss and Leonidas Stamatatos and James G Kublin and Dan H Barouch},
  journal={Journal of virology},
  year={2015},
  volume={89 4},
  pages={
          1965-74
        }
}
  • Hui-Wen Chang, Lawrence J Tartaglia, +10 authors Dan H Barouch
  • Published in Journal of virology 2015
  • Biology, Medicine
  • UNLABELLED The development of a panel of mucosally transmissible simian-human immunodeficiency virus (SHIV) challenge stocks from multiple virus clades would facilitate preclinical evaluation of candidate HIV-1 vaccines and therapeutics. The majority of SHIV stocks that have been generated to date have been derived from clade B HIV-1 env sequences from viruses isolated during chronic infection and typically required serial animal-to-animal adaptation for establishing mucosal transmissibility… CONTINUE READING

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