Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion.

@article{Ye2010GenerationAD,
  title={Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion.},
  author={Zhi-Jian Ye and Qiong Zhou and Yong-Yao Gu and Shou-ming Qin and Wan-Li Ma and Jian-bao Xin and Xiao-nan Tao and Huan-zhong Shi},
  journal={Journal of immunology},
  year={2010},
  volume={185 10},
  pages={6348-54}
}
IL-17-producing CD4(+) T (Th17) cells have been found to be increased in some human cancers; however, the possible implication of Th17 cells in regulating antitumor responses in malignant pleural effusion (MPE) remains to be elucidated. In the current study, distribution and phenotypic features of Th17 cells in both MPE and peripheral blood from patients with lung cancer were determined by flow cytometry or double immunofluorescence staining. The impacts of cytokines on Th17 cell generation and… CONTINUE READING
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