Generation and characterization of nanobodies targeting PSMA for molecular imaging of prostate cancer.

Abstract

Nanobodies show attractive characteristics for tumor targeting in cancer diagnosis and therapy. A radiolabeled nanobody binding the prostate-specific membrane antigen (PSMA) could offer a noninvasive strategy to select prostate cancer patients eligible for PSMA-targeted therapies. We here describe the generation, production and in vivo evaluation of anti… (More)
DOI: 10.1002/cmmi.1558

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