Generation and characterization of cardiomyocytes under serum-free conditions.

  title={Generation and characterization of cardiomyocytes under serum-free conditions.},
  author={Cornelia Gissel and Michael Xavier Doss and Rita Hippler-Altenburg and J{\"u}rgen Hescheler and Agapios Sachinidis},
  journal={Methods in molecular biology},
In vitro culturing of mammalian cells provides an elegant platform to study cell signaling, interactions, and metabolism as well as proliferation and differentiation processes. Often, these cells are cultured and maintained in sera obtained from animals such as horses, cows, and rabbits. The sera used for this purpose fluctuates in composition from individual animals and, hence, influences the cellular growth and differentiation at different magnitudes. This poses a need to use a substitute for… CONTINUE READING
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