Generation and characterization of P gene-deficient rabies virus.

@article{Shoji2004GenerationAC,
  title={Generation and characterization of P gene-deficient rabies virus.},
  author={Youko Shoji and Satoshi Inoue and Kazuo Nakamichi and Ichiro Kurane and Takeo Sakai and Kinjiro Morimoto},
  journal={Virology},
  year={2004},
  volume={318 1},
  pages={295-305}
}
Rabies virus (RV) deficient in the P gene was generated by reverse genetics from cDNA of HEP-Flury strain lacking the entire P gene. The defective virus was propagated and amplified by rescue of virus, using a cell line that complemented the functions of the deficient gene. The P gene-deficient (def-P) virus replicated its genome and produced progeny… CONTINUE READING