Generation and Characterization of a MYF5 Reporter Human iPS Cell Line Using CRISPR/Cas9 Mediated Homologous Recombination

@inproceedings{Wu2016GenerationAC,
  title={Generation and Characterization of a MYF5 Reporter Human iPS Cell Line Using CRISPR/Cas9 Mediated Homologous Recombination},
  author={Jianbo Wu and Samuel D. Hunt and Haipeng Xue and Ying Liu and Radbod Darabi},
  booktitle={Scientific reports},
  year={2016}
}
Human iPS cells hold great promise for disease modeling and treatment of degenerative disorders including muscular dystrophies. Although a few research groups have used them for skeletal muscle differentiation, most were based on gene over-expression or long-term mesenchymal differentiation and retrospective identification of myogenic cells. Therefore, this… CONTINUE READING
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