Generating the cerebral cortical area map.

  title={Generating the cerebral cortical area map.},
  author={Elizabeth Ann Grove and Tomomi Fukuchi-Shimogori},
  journal={Annual review of neuroscience},
The view that the cortical primordium is initially patterned in similar ways to the rest of the embryo has been a conceptual breakthrough. We now have a new starting point for understanding how the cortical area map is established and how maps may change and evolve. Here we review findings that signaling molecules secreted from distinct cortical signaling centers establish positional information in the cortical primordium and regulate regional growth. In other embryonic systems, positional… CONTINUE READING
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