Generalized morphea and primary biliary cirrhosis coexisting in a male patient

@article{GonzlezLpez2006GeneralizedMA,
  title={Generalized morphea and primary biliary cirrhosis coexisting in a male patient},
  author={Marcos Antonio Gonz{\'a}lez-L{\'o}pez and Marta Drake and M. carmen Gonzalez-vela and Susana Armesto and H{\'e}ctor F Llaca and Jos{\'e}-Fernando Val-Bernal},
  journal={The Journal of Dermatology},
  year={2006},
  volume={33}
}
We present further evidence that generalized morphea (GM) and primary biliary cirrhosis (PBC) may be associated. As far as we know, only six cases with this association have been previously reported in the published work, all of which were observed in women. We describe the case of a 62‐year‐old man diagnosed with M2‐antibody‐positive PBC who developed multiple generalized indurated plaques on the trunk and extremities 3 years later. Clinical history, laboratory data and histopathological… 
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Comorbidity of localized scleroderma and primary biliary cholangitis
  • G. Bali, A. Szilvási, B. Hidvégi
  • Medicine
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • 2018
TLDR
The objective of this case series was to study the possible association of morphea with PBC and to identify risk factors.
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Clinical hepatic disease did not occur in scleroderma patients, despite the relatively increased frequency of liver enzymes abnormalities, and autoantibodies in this disease were found to be low.
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