Generalized acanthosis nigricans.

Abstract

A patient suffering from an advanced and inoperable gastric carcinoma developed an unusual paraneoplastic syndrome, consisting of intensive pruritus, acanthosis nigricans, sign of Leser-Trélat (seborrhoic keratoses and freckles), warty and papillomatous excrescences, palmoplantar hyperkeratosis and florid papillomatous and granular lesions of the mouth… (More)

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