Generalized Seizure and Toxic Epidermal Necrolysis following Levofloxacin Exposure

  title={Generalized Seizure and Toxic Epidermal Necrolysis following Levofloxacin Exposure},
  author={Megan J Christie and Karen Wong and R. H. Ting and P. Tam and T. Sikaneta},
  journal={Annals of Pharmacotherapy},
  pages={953 - 955}
  • Megan J Christie, Karen Wong, +2 authors T. Sikaneta
  • Published 2005
  • Medicine
  • Annals of Pharmacotherapy
  • OBJECTIVE: To report the case of a ciprofloxacin-allergic patient who developed a generalized tonic—clonic seizure and toxic epidermal necrolysis (TEN) following a single dose of levofloxacin. CASE SUMMARY: An 87-year-old white woman was admitted to the hospital following a transient episode of unresponsiveness that had been accompanied by flailing of her limbs. Approximately 4 hours earlier, she had developed a pruritic rash on her trunk and limbs, and 3 hours before this had taken a first… CONTINUE READING
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