Generalized Anxiety Disorder, Comorbid Major Depression and Heart Rate Variability: A Case-Control Study in Taiwan

@inproceedings{Chang2013GeneralizedAD,
  title={Generalized Anxiety Disorder, Comorbid Major Depression and Heart Rate Variability: A Case-Control Study in Taiwan},
  author={Hsin-An Chang and Chuan-Chia Chang and Nian-Sheng Tzeng and Terry B. J. Kuo and Ru-Band Lu and San-Yuan Huang},
  booktitle={Psychiatry investigation},
  year={2013}
}
OBJECTIVE Decreased heart rate variability (HRV) has been reported in generalized anxiety disorder (GAD), but the results are mixed. Little is known about the impact of comorbid major depression (MD) on HRV in GAD patients. Both issues necessitate further investigation. METHODS Twenty unmedicated, physically healthy GAD patients, 20 GAD patients with a secondary diagnosis of MD, 40 MD patients and 60 matched controls were recruited. We used the Hamilton Anxiety Rating Scale and the Hamilton… CONTINUE READING
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