Generalized Adjacency in Genetic Networks and the Conservation of Functional Gene Clusters

Abstract

Given genetic networks derived from two genomes, it may be difficult to decide if their local structures are similar enough in both genomes to infer some ancestral configuration or some conserved functional relationships. Current methods all depend on searching for identical substructures. We explore a generalized vertex proximity criterion, and present… (More)
DOI: 10.1109/BIBM.2011.54

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