Generalization of Acquired Somatic Symptoms in Response to Odors: A Pavlovian Perspective on Multiple Chemical Sensitivity

@article{Devriese2000GeneralizationOA,
  title={Generalization of Acquired Somatic Symptoms in Response to Odors: A Pavlovian Perspective on Multiple Chemical Sensitivity},
  author={Stephan Devriese and Winnie Winters and Kris Stegen and Ilse Van Diest and Hendrik A F Veulemans and Benoit Nemery and Paul Eelen and Karel P. van de Woestijne and Omer Van den Bergh},
  journal={Psychosomatic Medicine},
  year={2000},
  volume={62},
  pages={751-759}
}
Objective Somatic symptoms that occur in response to odors can be acquired in a pavlovian conditioning paradigm. The present study investigated 1) whether learned symptoms can generalize to new odors, 2) whether the generalization gradient is linked to the affective or irritant quality of the new odors, and 3) whether the delay between acquisition and testing modulates generalization. Methods Conditional odor stimuli (CS) were (diluted) ammonia and niaouli. One odor was mixed with 7.4% CO2… Expand
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References

SHOWING 1-10 OF 59 REFERENCES
Acquisition and extinction of somatic symptoms in response to odours: a Pavlovian paradigm relevant to multiple chemical sensitivity.
TLDR
Subjects can acquire somatic symptoms and altered respiratory behaviour in response to harmless, but odorous chemical substances, if these odours have been associated with a physiological challenge that originally had caused these symptoms. Expand
Memory effects on symptom reporting in a respiratory learning paradigm.
TLDR
Attention manipulation showed that the learned complaints during the test phase were based on memory of the acquisition complaints and not on physiological responses during the tests, suggesting that physiological conditioning effects were not found. Expand
Respiratory learning and somatic complaints: a conditioning approach using CO2-enriched air inhalation.
TLDR
Correlational analyses showed that increases in complaints as caused by the conditioning procedure were predicted by changes in somatic variables, but not by individual differences in Negative Affectivity. Expand
Learning to have Psychosomatic Complaints: Conditioning of Respiratory Behavior and Somatic Complaints in Psychosomatic Patients
TLDR
Respiratory responses and psychosomatic complaints can be elicited by conditioned stimuli in a highly specific way and are relevant for disorders in which respiratory abnormalities and/or psychosodic complaints may play a role and for multiple chemical sensitivity. Expand
Fear-relevant images as conditioned stimuli for somatic complaints, respiratory behavior, and reduced end-tidal pCO2.
TLDR
The type of imagery had strong effects on symptoms and physiological responses, and a selective conditioning effect was also observed: CS+ imagery produced more symptoms and altered respiratory behavior compared with CS- imagery, but only in the fear-relevant script condition. Expand
Olfaction and Multiple Chemical Sensitivity
  • R. Doty
  • Medicine, Chemistry
  • Toxicology and industrial health
  • 1994
TLDR
This study suggests that MCS is associated with increased nasal airflow resistance, respiration rate, heart rate, and scores on the Beck Depression Inventory, but not with significant changes in odor detection threshold sensitivity to phenyl ethyl alcohol and methyl ethyl ketone, the two target stimuli evaluated. Expand
Negative affect, respiratory reactivity, and somatic complaints in a CO2 enriched air inhalation paradigm
TLDR
The pattern of results suggests that experimental inductions of complaints may largely wipe out NA-related differences in attentional/interpretative processes that may mediate the NA complaints link. Expand
An olfactory-limbic model of multiple chemical sensitivity syndrome: Possible relationships to kindling and affective spectrum disorders
TLDR
A model for MCS based on olfactory-limbic system dysfunction that overlaps in part with Post's kindling model for affective disorders is developed and raises testable neurobiological hypotheses that could increase understanding of the multifactorial etiology of MCS and of certain overlapping affective spectrum disorders. Expand
Time-dependent sensitization of heart rate and blood pressure over multiple laboratory sessions in elderly individuals with chemical odor intolerance.
TLDR
The data suggest that elderly individuals with a high degree of chemical odor intolerance evidence of increased sympathetic tone in the cardiovascular system at rest over multiple measurements and greater sensitizability and/or lesser habituation of heart rate and diastolic blood pressure over time as a function of repeated environmental stressor exposures. Expand
Preparedness and phobias: Specific evolved associations or a generalized expectancy bias?
Most phobias are focussed on a small number of fear-inducing stimuli (e.g., snakes, spiders). A review of the evidence supporting biological and cognitive explanations of this uneven distribution ofExpand
...
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4
5
...