Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.

@article{Waters2009GeneralizabilityOA,
  title={Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.},
  author={Kevin M. Waters and Lo{\"i}c Le Marchand and Laurence N. Kolonel and Kristine R Monroe and Daniel O. Stram and Brian E. Henderson and Christopher A. Haiman},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={2009},
  volume={18 4},
  pages={1285-9}
}
Genome-wide association studies have identified multiple common alleles associated with prostate cancer risk in populations of European ancestry. Testing these variants in other populations is needed to assess the generalizability of the associations and may guide fine-mapping efforts. We examined 13 of these risk variants in a multiethnic sample of 2,768 incident prostate cancer cases and 2,359 controls from the Multiethnic Cohort (African Americans, European Americans, Latinos, Japanese… CONTINUE READING

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Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2008

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