Generalised ceroid-lipofuscinosis and brown bowel syndrome in Cocker spaniel dogs.

@article{Jolly1994GeneralisedCA,
  title={Generalised ceroid-lipofuscinosis and brown bowel syndrome in Cocker spaniel dogs.},
  author={Robert W. Jolly and Winfield Hartley and Boyd Robert Jones and Alastair Campbell Johnstone and Anthony Claude Palmer and William F. Blakemore},
  journal={New Zealand veterinary journal},
  year={1994},
  volume={42 6},
  pages={
          236-9
        }
}
The ceroid-lipofuscinoses comprise a group of inherited storage diseases of human beings and animals that are characterised by progressive neurodegenerative disease and the accumulation within cells of a fluorescent lipopigment. A distinct syndrome occurs in Cocker spaniel dogs in which there is a generalised accumulation of a lipofuscin-like pigment, with such a heavy accumulation in smooth muscle that the intestine and other organs have a brown discolouration. Such discolouration is not… CONTINUE READING
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