General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.

@article{Zhao2013GeneralSO,
  title={General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.},
  author={Wen-Bo Zhao and Shinpei Nakagawa and Atsushi Kato and Isao Adachi and Yue-Mei Jia and Xiang-Guo Hu and George W J Fleet and Francis X. Wilson and Graeme Horne and Akihide Yoshihara and Ken Izumori and C. Yu},
  journal={The Journal of organic chemistry},
  year={2013},
  volume={78 7},
  pages={
          3208-21
        }
}
A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars. 
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