General solution for diffusion-controlled dissolution of spherical particles. 2. Evaluation of experimental data.

@article{Wang2002GeneralSF,
  title={General solution for diffusion-controlled dissolution of spherical particles. 2. Evaluation of experimental data.},
  author={Jianzhuo Wang and Douglas R. Flanagan},
  journal={Journal of pharmaceutical sciences},
  year={2002},
  volume={91 2},
  pages={534-42}
}
Our general particle dissolution model unified three traditional particle dissolution models and predicted that dissolution rates depend on surface curvature. Spherical benzocaine particles were prepared with a hot-melt dispersion method and physicochemically characterized. Their dissolution behavior was studied to evaluate the general dissolution model. A flow-through dissolution test system was used which employed an HPLC pump, an HPLC UV detector, a cylindrical-shaped dissolution cell, and a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…