General pharmacology of S 15261, a new concept for treatment of diabetes.

@article{Duhault1998GeneralPO,
  title={General pharmacology of S 15261, a new concept for treatment of diabetes.},
  author={Jacques L Duhault and Simona Berger and Mich{\`e}le Boulanger and Odile Della Zuana and F. Lacour and Michel Wierzbicki},
  journal={Arzneimittel-Forschung},
  year={1998},
  volume={48 7},
  pages={734-44}
}
The new compound S 15261 (CAS 159978-02-6) is the I-isomer of 3-[2-[2-[4-[2-(alpha-Fluorenylacetylamino)ethyl]benzoyloxy]ethylam ino]-1- methoxyethyl]trifluoromethylbenzene. The general synthetic pathway used for the preparation of S 15261 and related esters is given in this paper. This compound was selected for its promising therapeutical action on blood glucose, insulin resistance and associated risk factors present in patients with non-insulin-dependent Diabetes mellitus (NIDDM). The general… CONTINUE READING
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