Gene-transferring efficiencies of novel diamino cationic lipids with varied hydrocarbon chains.

@article{Kim2004GenetransferringEO,
  title={Gene-transferring efficiencies of novel diamino cationic lipids with varied hydrocarbon chains.},
  author={H. S. Kim and Jaeho Moon and K. Kim and M. M. Choi and J. Lee and Yeon Heo and D. H. Cho and D. O. Jang and Y. Park},
  journal={Bioconjugate chemistry},
  year={2004},
  volume={15 5},
  pages={
          1095-101
        }
}
  • H. S. Kim, Jaeho Moon, +6 authors Y. Park
  • Published 2004
  • Chemistry, Medicine
  • Bioconjugate chemistry
  • Utilizing three biocompatible components, a series of novel cationic lipids has been chemically synthesized and tested for their gene-transferring capabilities in 293 transformed kidney cells and B16BL6 mouse melanoma cells. The synthesized cationic lipids consisting of a core of lysine and aspartic acid with hydrocarbon chains of varied length were assigned the acronyms DLKD (O,O'-dilauryl N-lysylaspartate), DMKD (O,O'-dimyristyl N-lysylaspartate), DPKD (O,O'-dipalmityl N-lysylaspartate), and… CONTINUE READING
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