Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy.

@article{Griesenbach2009GeneTT,
  title={Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy.},
  author={Uta Griesenbach and Eric W. F. W. Alton},
  journal={Advanced drug delivery reviews},
  year={2009},
  volume={61 2},
  pages={128-39}
}
Gene therapy is currently being developed for a wide range of acute and chronic lung diseases. The target cells, and to a degree the extra and intra-cellular barriers, are disease-specific and over the past decade the gene therapy community has recognized that no one vector is good for all applications, but that the gene transfer agent (GTA) has to be carefully matched to the specific disease target. Gene therapy is particularly attractive for diseases that currently do not have satisfactory… CONTINUE READING

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