Gene transfer into rat brain using adenoviral vectors.

  title={Gene transfer into rat brain using adenoviral vectors.},
  author={Mariana Puntel and Kurt M. Kroeger and Nicholas Stephen Rennie Sanderson and Clare E. Thomas and Maria Graciela Castro and Pedro Ricardo Lowenstein},
  journal={Current protocols in neuroscience},
  volume={Chapter 4},
  pages={Unit 4.24}
Viral vector-mediated gene delivery is an attractive procedure for introducing genes into the brain, both for purposes of basic neuroscience research and to develop gene therapy for neurological diseases. Replication-defective adenoviruses possess many features which make them ideal vectors for this purpose-efficiently transducing terminally differentiated… CONTINUE READING