Gene transfer into coronary arteries of intact animals with a percutaneous balloon catheter.

@article{Chapman1992GeneTI,
  title={Gene transfer into coronary arteries of intact animals with a percutaneous balloon catheter.},
  author={Gregory D Chapman and Carol S Lim and R S Gammon and S C Culp and J S Desper and Robert P Bauman and J. L. Swain and Richard S Stack},
  journal={Circulation research},
  year={1992},
  volume={71 1},
  pages={27-33}
}
Genetic manipulation of the vasculature may offer insights into the pathogenesis of coronary artery disease and may lead to gene therapy for disorders such as restenosis after percutaneous coronary angioplasty. The goal of this study was to develop a percutaneous method for gene transfer into coronary arteries of intact animals. Liposomes were used to facilitate transfection in coronary arteries with a plasmid containing the cDNA encoding luciferase. This reporter was chosen since it is not… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Unstable Coronary Artery Syndromes Pathophysiology, Diagnosis and Treatment

Developments in Cardiovascular Medicine • 1998
View 7 Excerpts
Highly Influenced

Gene Therapy to Treat Cardiovascular Disease

Journal of the American Heart Association • 2013

Nanomedicine approaches in vascular disease: a review.

Nanomedicine : nanotechnology, biology, and medicine • 2011

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Anatomic propensity for restenosis following coronary angioplasty

JE Tcheng, DJ Frid, +5 authors RM Califf
J Am Coll Cardiol • 1991

Heart - toheart : New approaches for gene transfer in the myocardium

JJ Hunter, E Dyson
Circulation • 1991

Hormonal modulation of a gene injected into rat heart in vivo.

Proceedings of the National Academy of Sciences of the United States of America • 1991

Mechanical features of the Duke biodegradable intravascular stent . ( abstract )

RS Gammon, GD Chapman, +4 authors RS Stack
JAm Coll Cardiol • 1991

Restenosis after coronary angioplasty: an overview.

Journal of the American College of Cardiology • 1991

A bioabsorbable stent : Initial experimental results

GD Chapman, RS Gammon, +5 authors RS Stack
Circulation • 1990

A controlled trial of corticosteroids to prevent restenosis after coronary angioplasty

JA Hill, AA Bove, R Jugo
Circulation • 1990

Similar Papers

Loading similar papers…