Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization.


Direct gene transfer into localized arterial segments can be performed in vivo by transfection with DNA-liposome complexes. This technique holds promise for the treatment of human diseases, including malignancy and cardiovascular disorders. We have previously characterized the potential toxicity of this form of treatment in mice in vivo (Stewart et al… (More)


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