Gene transfer by means of lipo- and polyplexes: role of clathrin and caveolae-mediated endocytosis.

@article{Rejman2006GeneTB,
  title={Gene transfer by means of lipo- and polyplexes: role of clathrin and caveolae-mediated endocytosis.},
  author={Joanna Rejman and Massimo Conese and Dick Hoekstra},
  journal={Journal of liposome research},
  year={2006},
  volume={16 3},
  pages={237-47}
}
In this paper we address the contribution of different endocytic pathways to the intracellular uptake and processing of differently sized latex particles and of plasmid DNA complexes by means of fluorescence microscopy and FACS analysis. By using a number of specific inhibitors of either clathrin-dependent or caveolae-dependent endocytosis we were able to… CONTINUE READING