Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors

@article{Okada2003GeneTE,
  title={Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors},
  author={Naoki Okada and Yasushige Masunaga and Yuka Okada and Sayaka Iiyama and Naoki Mori and Takashi Tsuda and Asako Matsubara and Hiroyuki Mizuguchi and Takao Hayakawa and Takuya Fujita and Akira Yamamoto},
  journal={Cancer Gene Therapy},
  year={2003},
  volume={10},
  pages={421-431}
}
Since dendritic cells (DCs) play a critical role in establishing antigen-specific adaptive immune responses, in the past several years, therapeutic strategies using genetically modified DCs against cancer and infectious diseases have attracted increasing attention. In the present study, we demonstrated that RGD fiber-mutant adenovirus vector (AdRGD… CONTINUE READING