Gene therapy vectors based on adeno-associated virus type 1.

@article{Xiao1999GeneTV,
  title={Gene therapy vectors based on adeno-associated virus type 1.},
  author={Weidong Xiao and Narendra Chirmule and Scott C. Berta and Beth A. McCullough and Guang-ping Gao and James Michael Wilson},
  journal={Journal of virology},
  year={1999},
  volume={73 5},
  pages={3994-4003}
}
The complete sequence of adeno-associated virus type 1 (AAV-1) was defined. Its genome of 4,718 nucleotides demonstrates high homology with those of other AAV serotypes, including AAV-6, which appears to have arisen from homologous recombination between AAV-1 and AAV-2. Analysis of sera from nonhuman and human primates for neutralizing antibodies (NAB) against AAV-1 and AAV-2 revealed the following. (i) NAB to AAV-1 are more common than NAB to AAV-2 in nonhuman primates, while the reverse is… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
189 Extracted Citations
33 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 189 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…