Gene therapy on demand

  title={Gene therapy on demand},
  author={Alan W. Dove},
  journal={Nature Biotechnology},
  • A. Dove
  • Published 1 February 1999
  • Biology
  • Nature Biotechnology
New work by scientists from Florida State University, Tallahassee and the University of London’s Birkbeck College provides further insight into the mechanism of action of the anticancer drug Taxol and could facilitate the design of new drugs (J. Mol. Biol. 285:197–203, 1999). The cytoskeletal protein tubulin has long been known as a cellular target for Taxol, but it has been unclear how this interaction results in the death of cancer cells. Lee Makowski and his colleagues set out to identify…