Gene therapy of the ischemic lower limb--Therapeutic angiogenesis.

  title={Gene therapy of the ischemic lower limb--Therapeutic angiogenesis.},
  author={Vladimir Bobek and Oliver Taltynov and Daniela Pint{\'e}rov{\'a} and Katar{\'i}na Kolo{\vs}tov{\'a}},
  journal={Vascular pharmacology},
  volume={44 6},
The limitations of surgical revascularisation and pharmacological treatment in peripheral arterial occlusive disease (PAOD) are well recognized. Therapeutic options for critical leg ischemia are consequently limited to percutaneous transluminal angioplasty (PTA) or surgical revascularisation. Unfortunately, many patients with critical leg ischemia are poor candidates for either procedure. Therapeutic angiogenesis is a novel promising tool to treat these patients. Experimental and clinical and… CONTINUE READING