Gene therapy of prostate cancer: current and future directions.

  title={Gene therapy of prostate cancer: current and future directions.},
  author={Nicola J. Mabjeesh and Hong Zhong and Jonathan W. Simons},
  journal={Endocrine-related cancer},
  volume={9 2},
Prostate cancer (PCA) is the second most common cause of death from malignancy in American men. Developing new approaches for gene therapy for PCA is critical as there is no effective treatment for patients in the advanced stages of this disease. Current PCA gene therapy research strategies include cytoreductive approaches (immunotherapy and cytolytic/pro-apoptotic) and corrective approaches (replacing deleted or mutated genes). The prostate is ideal for gene therapy. It is an accessory organ… CONTINUE READING
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